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  • Title: Voice outcomes after radiotherapy treatment for early glottic cancer: assessment using multidimensional tools.
    Author: Bibby JR, Cotton SM, Perry A, Corry JF.
    Journal: Head Neck; 2008 May; 30(5):600-10. PubMed ID: 18098302.
    Abstract:
    BACKGROUND: This is the first prospective study to use instrumental and both clinician- and client-rated auditory-perceptual measures to examine voice and voice-related quality of life changes in patients after curative radiotherapy for early glottic cancer. METHOD: Thirty patients undergoing curative radiotherapy treatment for early glottic cancer completed the following: 3 voice tasks for acoustic, aerodynamic, and auditory-perceptual voice measures (therapist-rated); a patient self-report rating of voice quality; and a voice-related quality of life assessment before and 12 months after radiotherapy. RESULTS: Patients' perceptions of their voice quality and their voice-related quality of life significantly improved posttreatment, as did acoustic, aerodynamic, and auditory-perceptual voice measures. Mean speaking fundamental frequency did not change significantly, although breathiness and strain in the voice recordings were demonstrably reduced. CONCLUSION: In describing postradiotherapy voices in this study, pertinent measures of voice outcomes have been established, setting the benchmark for comparison in future cohort studies.
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