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  • Title: Glia maturation factor beta stimulates axon regeneration in transected rat sciatic nerve.
    Author: Harman K, Katnick J, Lim R, Zaheer A, de la Torre JC.
    Journal: Brain Res; 1991 Nov 15; 564(2):332-5. PubMed ID: 1810633.
    Abstract:
    Rat sciatic nerves were bilaterally transected and repaired with an entubulation technique. The nerve interstump gap was filled with either collagen gel or collagen gel mixed with a putative neurotrophic factor (leupeptin, 4-aminopyridine, lipid angiogenic factor or glia maturation factor beta (GMF-beta]. Six weeks after nerve transection, the myelinated distal stump axons were quantified for each nerve. Only the nerves treated with GMF-beta had significantly more axons than the control side.
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