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  • Title: Increasing infertility in myotonia dystrophica Curschmann-Steinert. A case report.
    Author: Hauser W, Aulitzky W, Baltaci S, Frick J.
    Journal: Eur Urol; 1991; 20(4):341-2. PubMed ID: 1814753.
    Abstract:
    A 26-year-old male came to our andrologic out-patient clinic because of his desire to have children. Preliminary examinations revealed a varicocele left and a subclinical varicocele right. Testicular volume was smaller than normal, and spermiogram values were already poor (vitality, motility and morphology). Basic hormones were normal. The anamnesis gave no information on hereditary disorders. Surgical treatment of the varicocele did not bring the desired outcome. A testicular biopsy showed Leydig cell hyperplasia with strongly reduced spermiohistogenesis. In a renewed and extensive anamnesis, the patient revealed that he suffers from myotonia dystrophica Curschmann-Steinert. This disorder causes sclerosis of the tubuli seminiferi contorti, which can ultimately lead to azoospermia.
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