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  • Title: [Lighting effect on spontaneous tumor development in female rats].
    Author: Vinogradova IA, Bukalev AV, Zabezhinskiĭ MA, Semenchenko AV, Anisimov VN.
    Journal: Vopr Onkol; 2007; 53(5):554-61. PubMed ID: 18154120.
    Abstract:
    The investigation is concerned with effects of lighting--12hr light/12hr dark (standard), natural lighting in the Russian North-West, constant illumination and light deprivation--on life span and spontaneous tumor development in female LIO rats. Constant and North-West lighting involved premature aging, shorter mean (13.5 and 25%) and maximum life span (by 9 and 7 months, respectively) and a significant increase in spontaneous tumor development rate as compared with standard lighting. Light deprivation resulted in a longer maximum life span and significant (2.1 times) drop in tumor incidence.
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