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  • Title: Case of seminoma with possible spontaneous regression without extragonadal metastatic lesion.
    Author: Minamida S, Irie A, Ishii J, Minei S, Kimura M, Iwamura M, Morinaga S.
    Journal: Urology; 2007 Dec; 70(6):1222.e1-3. PubMed ID: 18158054.
    Abstract:
    We present an extraordinarily rare finding of a testicular seminoma apparently in the process of spontaneous regression without accompanying metastatic lesion. A 35-year-old man visited our institute for persistent scrotal induration after the administration of antibiotics for several weeks. Ultrasonography and magnetic resonance imaging showed a capsulized tumor in his left atrophic testicle, without other visceral tumor or lymphadenopathy. We performed left radical orchiectomy. Histological examination revealed a fibrotic tumor with a small area of pure seminoma apparently undergoing spontaneous regression, and an intratubular germ cell neoplasia, unclassified, occurring diffusely. The patient is free of disease at 1 year after surgery.
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