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  • Title: [Erythrocytic membrane status (as cell model) in cases of severe cranium-face trauma: possibilities for correction].
    Author: Karmen NB, Miliutina NP, Zakarov AM, Maevskĭ EI, Ippolitov VP.
    Journal: Stomatologiia (Mosk); 2007; 86(5):15-9. PubMed ID: 18163056.
    Abstract:
    Acute posttraumatic period of severe maxillofacial trauma in case of hyperbaric oxygenation therapy is followed by expressed activation of lipide-peroxide-oxidation (LPO) in erythrocytic membrane on the background of significant reduction of the substrate for fermentative antioxidation system (AOS). Imbalance in the system LPO:AOS is followed by expressed structural reorganization in erythrocytic membrane and build-up extraerythrocytic haemoglobin in plasma. Klonidine promotes LPO activity reduction and prevents depletion of AOS fermentative capacity in membrane that is followed by normalization of structural-functional interrelations in membrane and reduction of the level of extraerythrocytic haemoglobin in plasma.
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