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  • Title: Clostridium difficile infection precipitating hemolysis in glucose-6-phosphate dehydrogenase-deficient preterm twins causing severe neonatal jaundice.
    Author: Lodha A, Kamaluddeen MS, Kelly E, Amin H.
    Journal: J Perinatol; 2008 Jan; 28(1):77-8. PubMed ID: 18165833.
    Abstract:
    The incidence of glucose-6-phosphate dehydrogenase deficiency in neonates of immigrant mothers in Canada is increasing. Newborn screening programs in Canada do not screen for this disorder. Infants with G-6-PD deficiency may develop jaundice resulting in kernicterus with devastating sequelae. In this case report, we speculate that Clostridium difficile infection may have triggered severe jaundice in G-6-PD-deficient neonates.
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