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  • Title: Disseminated herpes simplex type-2 (HSV-2) infection after solid-organ transplantation.
    Author: Basse G, Mengelle C, Kamar N, Ribes D, Selves J, Cointault O, Suc B, Rostaing L.
    Journal: Infection; 2008 Feb; 36(1):62-4. PubMed ID: 18165863.
    Abstract:
    We report on three cases of severe disseminated Herpes simplex type-2 (HSV-2) infection that occurred in two orthotopic liver-transplant (OLT) and one renal-transplant patients. In two cases, i.e., in the OLT patients, this was associated with HSV-2-related acute hepatitis. The rapid onset of IV acyclovir (ACV) therapy led to recovery within 8-12 days. Although rare, HSV-2-disseminated infection, in the context of organ transplantation may be life-threatening, but can be cured if ACV therapy is initiated early in the course of this disease.
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