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  • Title: Tight regulation of the Epstein-Barr virus setpoint: interindividual differences in Epstein-Barr virus DNA load are conserved after HIV infection.
    Author: Piriou E, van Dort K, Otto S, van Oers MH, van Baarle D.
    Journal: Clin Infect Dis; 2008 Jan 15; 46(2):313-6. PubMed ID: 18171268.
    Abstract:
    Healthy individuals carry a constant number of Epstein-Barr virus-infected B cells in the peripheral blood over time. Here, we show that interindividual differences in Epstein-Barr virus DNA levels are maintained after HIV infection, providing evidence for the existence of an individual Epstein-Barr virus setpoint. Immune activation may contribute to the increase in this setpoint after human immunodeficiency virus seroconversion.
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