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  • Title: [Variability of the response to recombinant human erythropoietin in patients undergoing hemodialysis treatment].
    Author: Baroni A, Airoldi G, Agliata S, Fortina F, Ragazzoni E, Cavagnino A, De Nigris A, Cametti G, Ferrero D, Fortina A.
    Journal: Minerva Urol Nefrol; 1991; 43(3):131-5. PubMed ID: 1817334.
    Abstract:
    The paper assesses the existence of possible interference between dialysis and the response to human recombinant erythropoietin administered i.v. in a group of patients undergoing regular dialysis. The results obtained show that the time taken to reach the set hemoglobin target (Hb 10 g%) was shorter in hemodiafiltered (HDF) patients compared to those receiving bicarbonate dialysis (BD). A plausible explantation may be the different depurative characteristics and the greater degree of biocompatibility of alternative dialysis which is able to achieve a more rapid cellular response to pharmacological stimulation.
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