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  • Title: An efficient synthesis and substitution of 3-aroyl-2-bromobenzo[b]furans.
    Author: Gill GS, Grobelny DW, Chaplin JH, Flynn BL.
    Journal: J Org Chem; 2008 Feb 01; 73(3):1131-4. PubMed ID: 18177049.
    Abstract:
    A convenient method for the synthesis of 2-bromo-3-aroyl-benzo[b]furans from readily accessible precursors has been developed. The 2-bromo group has been employed as a versatile synthetic handle in both palladium-mediated couplings and direct nucleophilic substitutions to give access to a wide range of 2-substituted-3-aroyl-benzo[b]furans.
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