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  • Title: Update for nurse anesthetists--part 5--Transfusion-related acute lung injury.
    Author: Joyce JA.
    Journal: AANA J; 2007 Dec; 75(6):437-44. PubMed ID: 18179004.
    Abstract:
    Acute onset of dyspnea, fever, hypotension, and cough during or soon after a blood or blood-product transfusion has been described in the literature since the early 1950s. Between 2003 and 2005, transfusion-related acute lung injury (TRALI) surpassed ABO incompatibility as the number one cause of transfusion-related mortality in the United States, as reported to the Food and Drug Administration. Prompt recognition and appropriate intervention are required to reduce mortality. Prevention of TRALI represents a complex challenge. There is no single intervention that will prevent every case of TRALI, but several interventions have been proposed to reduce the risk.
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