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  • Title: Two cases of post-radiation osteosarcoma of the sacrum after pelvic irradiation for uterine cervical cancer.
    Author: Noh JM, Huh SJ.
    Journal: Eur J Gynaecol Oncol; 2007; 28(6):497-500. PubMed ID: 18179145.
    Abstract:
    BACKGROUND: Post-radiation pelvic bone sarcoma can result as a long-term sequela of pelvic irradiation for uterine cervical cancer. CASE: A 59-year-old woman who had received pelvic irradiation for Stage IIB uterine cervical cancer 16 years before was diagnosed as having post-radiation osteosarcoma of the sacrum. Another 66-year-old woman who had received pelvic irradiation for Stage IIIB uterine cervical cancer seven years previously was also diagnosed as having pleomorphic sarcoma of the sacrum. CONCLUSION: When a bone lesion is observed at a previously irradiated field, post-radiation sarcoma should be considered and differentiated from bone metastases.
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