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  • Title: A light-controlled reversible DNA photoligation via carbazole-tethered 5-carboxyvinyluracil.
    Author: Fujimoto K, Yoshino H, Ami T, Yoshimura Y, Saito I.
    Journal: Org Lett; 2008 Feb 07; 10(3):397-400. PubMed ID: 18181634.
    Abstract:
    We describe a light-controlled template-directed reversible DNA photoligation via carbazole-tethered 5-carboxyvinyluracil. Carbazole-tethered 5-carboxyvinyl-2'-deoxyuridine-containing oligodeoxynucleotide (ODN) can be ligated by irradiation at 366 nm in the presence of template ODN, and the ligated ODN can be split by irradiation at 366 nm in the absence of template ODN.
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