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  • Title: Regulation of T helper 17 differentiation by orphan nuclear receptors: it's not just ROR gamma t anymore.
    Author: Sundrud MS, Rao A.
    Journal: Immunity; 2008 Jan; 28(1):5-7. PubMed ID: 18199410.
    Abstract:
    T cells that produce IL-17 (T helper 17 cells) are implicated in autoimmune pathogenesis. In this issue of Immunity, Yang et al. (2008) report that the closely related orphan nuclear receptors ROR alpha and ROR gamma t work together to regulate T helper (Th)17 cell differentiation.
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