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  • Title: Intradermal antityphoid-antitetanus vaccination by jet injection.
    Author: Dimache G, Croitoru M, Velea V, Stoean C, Durbacă S, Mihăilescu M, Dimache A.
    Journal: Roum Arch Microbiol Immunol; 1991; 50(2):127-35. PubMed ID: 1820189.
    Abstract:
    A lyophilized, heat-killed, phenol preserved typhoid vaccine (5 x 10(8) cells) suspended in 0.1 ml unadsorbed concentrated tetanus vaccine (10 Lf) was administered in man by intradermal route. This association of the two vaccines resulted in milder postvaccinal reactions: moreover, the immunological properties of typhoid vaccine, as certified by the passive protection test of the mouse with sera of the vaccines and the H and O agglutinin titres found in these immune sera, were perfectly conserved. Consequently, the mixed typhoid-tetanus vaccination in man by intradermal route is possible and advantageous for practical and economical reasons.
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