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  • Title: Determination of the dietary absorption efficiency of hexachlorobenzene with the channel catfish (Ictalurus punctatus).
    Author: Woodburn KB, Marino TA, McClymont EL, Rick DL.
    Journal: Ecotoxicol Environ Saf; 2008 Oct; 71(2):419-25. PubMed ID: 18207240.
    Abstract:
    This study was designed to experimentally measure the assimilation efficiency of hexachlorobenzene (HCB) in a warm-water, benthic-feeding fish species, the channel catfish (Ictalurus punctatus). Catfish were exposed to (14)C-radiolabeled HCB in catfish food over a 28-day exposure period, followed by a 14-day clearance period. Over the experimental period, the total (14)C residues were measured in fish tissue and a simple two-box kinetic model was applied to the data to simulate uptake and clearance dynamics. No detectable metabolism of HCB by catfish was found. A two-box kinetic model effectively modeled the uptake and clearance of (14)C-HCB in catfish, with a calculated assimilation efficiency of the chemical into the whole catfish of 67% (growth corrected). The growth-corrected pseudo first-order elimination half-life of (14)C-HCB from whole catfish was determined to be 29 days (k(2)=0.024 day(-1)).
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