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  • Title: [Role of PET-CT with 18-FDG in the management of UADT squamous-cell carcinomas: a retrospective study of 43 cases].
    Author: Ricard AS, Gindre A, Laurentjoye M, Fernandez P, Guyot M, Demeaux H, Siberchicot F, Majoufre-Lefebvre C.
    Journal: Rev Stomatol Chir Maxillofac; 2008 Apr; 109(2):86-90. PubMed ID: 18207477.
    Abstract:
    INTRODUCTION: The aim of our retrospective study was to evaluate the role of PET-CT in the management of upper-aerodigestive tract (UADT) squamous-cell carcinomas. MATERIAL AND METHODS: Our study included 43 patients with UADT squamous-cell carcinomas having undergone PET-CT for: initial staging (n=20), diagnosis of recurrent disease (n=16), and response to treatment (n=7). RESULTS: PET-CT diagnosed distant metastases missed by conventional imaging in four patients (20%) in initial staging, four patients (25%) in diagnosis of recurrent disease, and two patients (29%) in response to treatment. Overall, PET-CT induced a shift in the management of 10 patients (28%). DISCUSSION: Our study and other publications suggest that PET-CT should be used in: initial staging in Stage III and IV; detection of recurrent disease; and evaluation of treatment response.
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