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  • Title: Influence of low-dose daily cisplatin on the distant metastasis-free survival of patients with locally advanced nonmetastatic head and neck cancer treated with radiation therapy.
    Author: Jeremić B, Milicić B.
    Journal: Radiother Oncol; 2008 May; 87(2):201-3. PubMed ID: 18207598.
    Abstract:
    We investigated the impact of low dose daily cisplatin on distant metastasis-free survival (DMFS) in locally advanced head and neck cancer treated with hyperfractionated radiotherapy (77Gy in 70 fractions in 35 treatment days). In locally controlled tumors cisplatin led to better DMFS (p=0.0272); Cisplatin may have acted independently of micrometastasis in locally advanced H&N cancer.
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