These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: [Growth follow-up of SGA children after 3 years of GH treatment].
    Author: Edouard T, Oliver I, Jouret B, Lounis N, Moulin P, Pienkowski C, Elefterion M, Salles JP, Tauber M.
    Journal: Arch Pediatr; 2008 Feb; 15(2):115-21. PubMed ID: 18207714.
    Abstract:
    UNLABELLED: Eighty-five percent of children born with IUGR have spontaneous catch-up growth in the first 2 years of life; however, about 10 to 15% do not catch up. Numerous therapeutic trials have demonstrated the efficacy of GH treatment in these children. However, the duration of this treatment is still discussed. OBJECTIVE: The aim of this study was to describe the evolution of growth during and after the end of treatment. POPULATION AND METHODS: This study followed 33 children in our unit, treated with growth hormone under the French indication (3 years of treatment followed by 1 year off treatment) and with a mean follow-up of 3 years after cessation. RESULTS: During the 3 years of therapy, we confirmed an increase in growth velocity that resulted in a mean height above -2 standard deviation score (SDS) in 25 children at 3 years (mean height of 1.4 SDS). Among the 25 children who achieved a height above -2 SDS at three years and therefore stopped treatment, 15 resumed GH due to a secondary catch-down. Among children who didn't catch-up at 3 years, the continuation of GH treatment didn't seem to improve the growth.
    [Abstract] [Full Text] [Related] [New Search]