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  • Title: Two cases of Zoon's balanitis treated with pimecrolimus 1% cream.
    Author: Bardazzi F, Antonucci A, Savoia F, Balestri R.
    Journal: Int J Dermatol; 2008 Feb; 47(2):198-201. PubMed ID: 18211499.
    Abstract:
    BACKGROUND: Plasma cell balanitis is a disorder of the middle-aged and older uncircumcised male. Several treatments have been proposed to treat this disease, but plasma cell balanitis is often resistant to conventional therapy. METHODS: We decided to evaluate the efficacy and tolerability of pimecrolimus 1% cream in resistant Zoon's balanitis. We report two cases of resistant Zoon's balanitis treated with topical pimecrolimus 1% cream. RESULTS: One of the two patients had a complete regression of the lesion after 2 months of therapy. The other one had a great improvement of the lesion, but a hyperpigmented patch persisted on the glans. CONCLUSION: Pimecrolimus 1% cream may be a valuable second-line treatment for patients with steroid related side effects or with steroid and other conventional therapy resistant Zoon's balanitis, as well as for those rejecting circumcision.
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