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  • Title: Dipeptide preparation Noopept prevents scopolamine-induced deficit of spatial memory in BALB/c mice.
    Author: Belnik AP, Ostrovskaya RU, Poletaeva II.
    Journal: Bull Exp Biol Med; 2007 Apr; 143(4):431-3. PubMed ID: 18214292.
    Abstract:
    The effect of original nootropic preparation Noopept on learning and long-term memory was studied with BALB/c mice. Scopolamine (1 mg/kg) impaired long-term memory trace, while Noopept (0.5 mg/kg) had no significant effect. Noopept completely prevented the development of cognitive disorders induced by scopolamine (blockade of muscarinic cholinergic receptors). Our results confirmed the presence of choline-positive effect in dipeptide piracetam analogue Noopept on retrieval of learned skill of finding a submerged platform (spatial memory). We conclude that the effectiveness of this drug should be evaluated in patients with Alzheimer's disease.
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