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  • Title: Effect of dimethylsulfoxide on the functions of mesenchymal and hemopoietic precursors.
    Author: Zyuz'kov GN, Gur'yantseva LA, Simanina EV, Zhdanov VV, Dygai AM, Goldberg ED.
    Journal: Bull Exp Biol Med; 2007 Apr; 143(4):535-8. PubMed ID: 18214317.
    Abstract:
    The effects of dimethylsulfoxide on the state of mesenchymal precursors in vivo were demonstrated. Treatment with dimethylsulfoxide reduced the content of stromal clonogenic elements in the bone marrow and inhibited mobilization of mesenchymal precursors induced by granulocyte colony-stimulating factor. In in vitro system, dimethylsulfoxide inhibited proliferation of fibroblast, erythroid, and granulomonocytic colony-forming units and stimulates maturation of hemopoietic precursors.
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