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  • Title: Pan-steatitis in farmed northern bluefin tuna, Thunnus thynnus (L.), in the eastern Adriatic.
    Author: Roberts RJ, Agius C.
    Journal: J Fish Dis; 2008 Feb; 31(2):83-8. PubMed ID: 18234015.
    Abstract:
    Clinical, gross and histopathological investigations were carried out into large-scale mortalities on eastern Mediterranean bluefin tuna, Thunnus thynnus (L.), farms. Fish showed only nervous signs and darkened colour. At post-mortem the liver was bronze coloured and the pyloric area waxy in consistency. There was no evidence of any other gross pathology. Histopathology showed severe hepatic necrosis and lipidosis. Peri-pancreatic lipoid tissue was heavily infiltrated with an inflammatory round cell infiltrate. Fish on all three farms had been fed on a North African pilchard diet rather than traditional local or Baltic species. Once the diet was modified, losses ceased. A diagnosis of pan-steatitis as seen in other farmed fish species, as well as in terrestrial animals, on particular fish-based diets was made, although the actual factor within the diet which induced the inflammatory effect is not known.
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