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  • Title: Homozygous alpha-thalassemia in a growth retarded, non-hydropic premature newborn.
    Author: Ng YP, Joseph R, Biswas A.
    Journal: J Perinatol; 2008 Feb; 28(2):158-9. PubMed ID: 18235510.
    Abstract:
    A newborn with homozygous alpha-thalassemia presented with intrauterine growth retardation and presumed persistent pulmonary hypertension. He also had moderate anemia, hepatomegaly and hypospadias. Correlating the newborn's clinical presentation with an underlying cause of anemia was helpful for early diagnosis. Prenatal blood tests must include red cell indices and a mean corpuscular volume value below 80 fL should prompt thalassemia screening in an at-risk population.
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