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  • Title: [Preparation and characterization of solid lipid nanoparticles of norcantharidin].
    Author: Tian HY, Zhai GX.
    Journal: Zhong Yao Cai; 2007 Sep; 30(9):1146-8. PubMed ID: 18236763.
    Abstract:
    OBJECTIVE: To prepare and characterize the solid lipid nanoparticles containing norcantharidin. METHODS: Entrapment efficiency was studied to choose the best method of preparing norcantharidin solid lipid nanoparticles. The physico-chemical properties of norcantharidin solid lipid nanoparticles were investigated. RESULTS: The entrapment efficiency of norcantharidin in solid lipid nanoparticles was 54.6%, the average particle diameter was 190 nm, and it was stable at 4 degrees C for 3 months. CONCLUSION: Solid lipid nanoparticles of norcantharidin prepared has high entrapment efficiency and good stability.
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