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  • Title: [Studies on pyridonecarboxylic acids as antibacterial agents. X. Synthesis and structure-activity relationships of 1, 7-disubstituted-6-fluoro-1,4-dihydro-4-oxo-quinoline-3-carboxylic acids].
    Author: Chen JX, Guo HY.
    Journal: Yao Xue Xue Bao; 1991; 26(10):733-40. PubMed ID: 1823714.
    Abstract:
    A series of pyridonecarboxylic acids were prepared. These compounds have different groups including substituted benzenes, furans and isoxazles at the 1-position, or different substituted amino groups at the 7-position. The in vitro antibacterial potencies of these compounds against E. coli. and S. aureus were tested, and structure-activity relationships were discussed.
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