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  • Title: Pulmonary synovial sarcoma presenting as a pneumothorax during pregnancy.
    Author: Esaka EJ, Celebrezze JU, Golde SH, Chiossi G, Thomas RL.
    Journal: Obstet Gynecol; 2008 Feb; 111(2 Pt 2):555-8. PubMed ID: 18239021.
    Abstract:
    BACKGROUND: Synovial sarcoma is a clinically rare, but morphologically well-defined neoplasm, which accounts for approximately 10% of all malignant soft-tissue tumors. The diagnosis can be established with clinical and imaging evaluations together with immunohistochemical, electron microscopy, and molecular genetic studies. CASE: We describe a case of primary pulmonary synovial sarcoma presenting as a pneumothorax in a young woman at 34 weeks of gestation. Her persistent symptomatology ultimately led to a video-assisted thoracoscopy and thorascopic decortication. The diagnosis was established by pathology and immunohistochemistry of the cells, which were consistent with primary pulmonary synovial sarcoma. CONCLUSION: Malignancies, even those as uncommon as primary synovial sarcoma, should be considered in the differential diagnosis of pneumothorax during pregnancy.
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