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  • Title: Pathogenesis of Machupo virus infection in primates.
    Author: Eddy GA, Scott SK, Wagner FS, Brand OM.
    Journal: Bull World Health Organ; 1975; 52(4-6):517-21. PubMed ID: 182402.
    Abstract:
    Experimental Machupo virus infection of rhesus and cynomolgus monkeys produced a severe illness consisting of an initial clinical phase and a later neurological phase. Cumulative mortality during the two phases was 80% and 95% respectively. Attempts to alter the pathogenesis with decomplementation or immunosuppression resulted in earlier deaths of the monkeys.
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