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  • Title: Effect of chitin/silk fibroin nanofibrous bicomponent structures on interaction with human epidermal keratinocytes.
    Author: Yoo CR, Yeo IS, Park KE, Park JH, Lee SJ, Park WH, Min BM.
    Journal: Int J Biol Macromol; 2008 May 01; 42(4):324-34. PubMed ID: 18243300.
    Abstract:
    To fabricate a biomimetic nanostructured bicomponent scaffolds, two types of chitin/silk fibroin (SF) nanofibrous scaffolds (blend scaffolds and hybrid scaffolds) were prepared by electrospinning or simultaneous electrospinning of chitin/SF solutions. The chitin/SF bicomponent scaffolds were after-treated with water vapor, and their nanofibrous structures were almost maintained. From the cytocompatibility and cell behavior on the chitin/SF blend or hybrid nanofibrous scaffolds, the hybrid matrix with 25% chitin and 75% SF as well as the chitin/SF blend nanofibers could be a potential candidate for tissue engineering scaffolds.
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