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  • Title: [Cloning and analysis of adenine nucleotide translocase gene in Helicoverpa armigera].
    Author: Niu BL, Weng HB, He LH, Shen WF, Qi XP, Liu Y, Meng ZQ.
    Journal: Yi Chuan; 2008 Jan; 30(1):81-6. PubMed ID: 18244907.
    Abstract:
    A cDNA clone encoding the ADP/ATP translocase in Helicoverpa armigera has been identified by RT-PCR, 5'and 3'RACE methods. Sequence analysis shows that it is 1,190 bp long and contains a single open reading frame (ORF, 133-1,033 bp) encoding a protein of 300 amino acids (GenBank submission number, AY253868). The protein has a 22 aa signal peptide on its N-terminal, which leads the protein locating onto the inner membrane of the mitochondria. It also has three conserved domains of the mitochondrial carrier protein forming a channel to exchange ATP and ADP energy molecule through the inner membrane of the mitochondria. It shows extensive similarities to the known ADP/ATP translocase poly-peptides. The ADP/ATP translocase similarity was up to 90% in the Lepidoptera.
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