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  • Title: [Characterization of nucleolar organizers in carcinomatous mammmary lesions].
    Author: Kharrat A, Krichen H, Tabbene F, Sellami M.
    Journal: Arch Inst Pasteur Tunis; 1991; 68(3-4):243-9. PubMed ID: 1824505.
    Abstract:
    An argyrophil stain for nucleolar organizer regions (NORs) has been applied to paraffin sections of 24 malignant and 3 benign breast tumors. It was found that the total number of Ag-NORs in malignant breast lesions (3.66) significantly exceeded those in benign lesions (1.65). Relationship between this index and some clinical parameters was studied. A positive correlation between NORs and histological grading and prognostic was found.
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