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  • Title: Silver-catalyzed benzylation and allylation reactions of tertiary and secondary alkyl halides with grignard reagents.
    Author: Someya H, Ohmiya H, Yorimitsu H, Oshima K.
    Journal: Org Lett; 2008 Mar 06; 10(5):969-71. PubMed ID: 18247499.
    Abstract:
    Treatment of alkyl halides, including tertiary alkyl bromides, with benzylic or allylic Grignard reagent in the presence of a catalytic amount of silver nitrate in ether yielded the corresponding cross-coupling products in high yields. The coupling reactions of tertiary alkyl halides provide efficient access to quaternary carbon centers.
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