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  • Title: Oral adenoviral-based vaccines: historical perspective and future opportunity.
    Author: Tucker SN, Tingley DW, Scallan CD.
    Journal: Expert Rev Vaccines; 2008 Feb; 7(1):25-31. PubMed ID: 18251691.
    Abstract:
    Adenoviral vaccines delivered orally have been used for decades to prevent respiratory illness, but are now being seriously explored again as a platform technology to make vaccines against a variety of pathogens. Years of use in military populations as a preventative measure for adenoviral infection have demonstrated the safety of oral administration of adenovirus. The advantages of using this approach as a platform technology for vaccines include rapid development and distribution, as well as ease of administration. Recent discoveries may allow this platform approach to reach the clinic within a few years.
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