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  • Title: [Periodic fever--two children with periodic fever, aphthous stomatitis pharyngitis, adenitis syndrome].
    Author: Mikkelsen TS, Tilma KA.
    Journal: Ugeskr Laeger; 2008 Feb 04; 170(6):461. PubMed ID: 18252184.
    Abstract:
    PFAPA (periodic fever, aphthous stomatitis, pharyngitis, adenitis) syndrome is characterised by episodes of fever (>40 degrees C), lasting 4-5 days and recurring every 3-6 weeks, accompanied by aphthous stomatitis, pharyngitis or cervical adenitis. Between the episodes of fever there are no symptoms. Glucocorticoids are highly effective in controlling the symptoms, while tonsillectomy results in remission. We describe two children with PFAPA syndrome. Early diagnosis can significantly improve the patients' quality of life.
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