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Title: [3 + 2] Cycloaddition reactions in the synthesis of triazolo[4,5-b]pyridin-5-ones and pyrrolo[3,4-b]pyridin-2-ones. Author: Gao Y, Lam Y. Journal: J Comb Chem; 2008; 10(2):327-32. PubMed ID: 18260650. Abstract: The reaction of 5-benzenesulfonyl-3,4-dihydro-1 H-pyridin-2-one derivatives with azides or isocyanides provided two new classes of compounds, triazolo[4,5-b]pyridin-5-ones 3 or pyrrolo[3,4-b]pyridin-2-ones 4, respectively, in good yields and regioselectivity. A representative set of 20 compound 3 and 12 compound 4 was prepared.[Abstract] [Full Text] [Related] [New Search]