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  • Title: [Acute coronary syndrome induced by hypoglycemia in the course of insulinoma--a case report].
    Author: Curzytek A, Gutkowski K, Barwinek J, Widuliński A, Bilkiewicz T, Lubas W, Guz W.
    Journal: Kardiol Pol; 2008 Jan; 66(1):67-9. PubMed ID: 18266188.
    Abstract:
    Insulinoma is the most frequent endocrine tumour of the pancreas derived from the beta cells which, while retaining the ability to synthesise and secrete insulin, is autonomous from the normal feedback mechanisms. The characteristic clinical manifestation of this neoplasm is fasting hypoglycaemia, with sympathoadrenal and neuroglycopenic symptoms. In extremely rare cases insulinoma can be a cause of acute coronary syndrome. Surgical removal is the treatment of choice and recurrences are uncommon. We report a case of a 74-year-old man with acute coronary syndrome caused by adrenergic stimulation during severe hypoglycaemic seizures in the course of insulinoma.
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