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  • Title: Calciotropic and magnesiotropic TRP channels.
    Author: Hoenderop JG, Bindels RJ.
    Journal: Physiology (Bethesda); 2008 Feb; 23():32-40. PubMed ID: 18268363.
    Abstract:
    Significant progress has been made into our understanding of the molecular mechanisms responsible for Ca2+ and Mg2+ homeostasis. Members of the transient receptor potential channel (TRP) superfamily proved essential to the maintenance of divalent cation levels by regulating their absorption from renal and intestinal lumina. This review highlights the molecular and functional aspects of these new calciotropic and magnesiotropic TRPs in health and disease.
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