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  • Title: Ovarian hyperstimulation syndrome caused by an FSH-secreting pituitary adenoma.
    Author: Cooper O, Geller JL, Melmed S.
    Journal: Nat Clin Pract Endocrinol Metab; 2008 Apr; 4(4):234-8. PubMed ID: 18268519.
    Abstract:
    BACKGROUND: A 40-year-old woman presented with galactorrhea and oligomenorrhea. She had a history of multiple ovarian cysts and pelvic pain. INVESTIGATIONS: Laboratory evaluation included measurements of the levels of estradiol, follicle-stimulating hormone, luteinizing hormone, prolactin, thyroid-stimulating hormone, free endogenous T4, the glycoprotein hormone alpha subunit, cortisol, adrenocorticotropic hormone, and insulin-like growth factor I. Radiological studies included MRI of the pituitary. DIAGNOSIS: Ovarian hyperstimulation syndrome caused by a pituitary adenoma, secreting follicle-stimulating hormone. MANAGEMENT: The patient underwent trans-sphenoidal resection of the adenoma, with subsequent normalization of hormonal values and symptoms.
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