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  • Title: Waveform diversity based ultrasound system for hyperthermia treatment of breast cancer.
    Author: Guo B, Li J.
    Journal: IEEE Trans Biomed Eng; 2008 Feb; 55(2 Pt 2):822-6. PubMed ID: 18270027.
    Abstract:
    In this letter, we present a new waveform-diversity-based ultrasound hyperthermia technique for the treatment of breast cancer. Waveform diversity offers a new paradigm for beampattern design. By choosing a proper covariance matrix of the transmitted waveforms under the uniform elemental power constraint, the ultrasound system can provide a focal spot matched to the entire tumor region, and meanwhile, minimize the impact to the surrounding healthy breast tissues. As shown in our 2-D numerical simulations, this method has better acoustic power deposition than the existing methods, and can provide the necessary temperature gradients required for the effective hyperthermia treatment of breast cancer.
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