These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: The poly(ADP-ribosylation) story: a long route from Cinderella to Princess.
    Author: Scovassi AI.
    Journal: Riv Biol; 2007; 100(3):351-60. PubMed ID: 18278737.
    Abstract:
    Poly(ADP-ribosylation) is a post-translational modification of proteins with a multifunctional role in basic processes, such as DNA repair, transcription, cell proliferation and death. For decades, this reaction was studied by a small community of researchers, devoted to the identification of signals promoting the conversion of the coenzyme NAD into poly(ADP-ribose) and the further degradation of the polymers. The development of specific inhibitors and the discovery of a superfamily of poly(ADP-ribosylating) enzymes have recently conferred a higher importance to this process. The main features of poly(ADP-ribosylation) together with new research perspectives will be discussed.
    [Abstract] [Full Text] [Related] [New Search]