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Title: Automatic core needle biopsy: a diagnostic option for head and neck masses. Author: Nyquist GG, Tom WD, Mui S. Journal: Arch Otolaryngol Head Neck Surg; 2008 Feb; 134(2):184-9. PubMed ID: 18283162. Abstract: OBJECTIVE: To examine the role of core needle biopsy in the diagnosis of head and neck masses. DESIGN: Prospective observational study. SETTING: The otolaryngology-head and neck surgery department outpatient clinic of a large managed care organization. PATIENTS: The study population comprised 40 consecutive patients referred for core needle biopsy of a cervicofacial lesion for which previous fine-needle aspiration biopsy had not provided the diagnosis. INTERVENTION: Manually guided Delta Cut (Boston Scientific, Natick, Massachusetts) core needle biopsy was performed on neck masses larger than 1.5 cm. MAIN OUTCOME MEASURE: Diagnosis was indicated by core needle biopsy results without excisional biopsy. RESULTS: A core needle biopsy specimen sufficient for diagnosis and treatment was obtained from 36 of the 40 patients (90%). In 22 patients, subsequent excisional biopsy or curative surgery was performed after core needle biopsy, and pathologic examination confirmed the diagnosis for 19 of these 22 patients (86%). For 12 of the remaining 14 patients (86%), core needle biopsy was successfully used to diagnose lymphoma. No complications resulted from the core needle biopsy. CONCLUSIONS: For lesions that require immunohistochemical staining or that remain undiagnosed after fine-needle aspiration, use of core needle biopsy should be considered before excisional biopsy. Core needle biopsy is a safe, effective, time-efficient, inexpensive procedure that can be an important tool for diagnosing head and neck masses, especially when lymphoma is suspected.[Abstract] [Full Text] [Related] [New Search]