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  • Title: Reflux oesophagitis in Italy (Diomede project).
    Author: Baldi F, Cavoli C, Solimando R, Bianco MA, Cipolletta L, Costamagna G, Passaretti S.
    Journal: Dig Liver Dis; 2008 Jun; 40(6):405-11. PubMed ID: 18294931.
    Abstract:
    AIMS: A multicentric observational study was performed to update the available information on reflux oesophagitis in Italy. METHODS: In phase I, the number and severity of reflux oesophagitis diagnosed in 1 year (2003) were reported together with the associated endoscopic findings. In phase II, oesophagitis patients consecutively referred in a 3-month period were analysed. A multivariate analysis was used to identify the risk factors for severe oesophagitis. RESULTS: 253,992 upper endoscopies were collected. The overall prevalence of oesophagitis was 14.8% and the endoscopic findings associated with oesophagitis were hiatus hernia (46.3%), duodenal ulcer (10.7%), gastric ulcer (3.6%) and Barrett's oesophagus (2.9%). In phase II, 1542 reflux oesophagitis patients were analysed (60.3% males; mean age 50.7 +/-16.6 years). Only 53.4% of patients reported heartburn and/or regurgitation as main complaint. Severe symptoms, age > 50 years, hiatus hernia and male gender were identified as independent predictors of severe oesophagitis. CONCLUSIONS: Oesophagitis is the most frequent among the peptic diseases of the upper gastro-intestinal tract. Only half of the oesophagitis patients reported typical reflux symptoms as dominant. Advanced age, male gender, severe symptoms and hiatus hernia were independent risk factors for severe disease.
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