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Title: Cytotoxic hydrolyzable tannins from Balanophora japonica. Author: Jiang ZH, Wen XY, Tanaka T, Wu SY, Liu Z, Iwata H, Hirose Y, Wu S, Kouno I. Journal: J Nat Prod; 2008 Apr; 71(4):719-23. PubMed ID: 18302336. Abstract: Four hydrolyzable tannins named balanophotannins D-G ( 1- 4) were isolated from the aerial parts of the parasitic plant Balanophora japonica. Their structures were characterized on the basis of spectroscopic and chemical evidence. Balanophotannins D-G contain an oxidized hexahydroxydiphenoyl (HHDP) group. The absolute configurations of balanophotannins D ( 1) and F ( 3) were determined via the PGME method. Balanophotannin E ( 2) showed cytotoxicity to Hep G2 cancer cells with an IC 50 value of 4.22 microM.[Abstract] [Full Text] [Related] [New Search]