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  • Title: The use of continuous subcutaneous octreotide infusion in brittle type 1 diabetic patients.
    Author: Bello F, Falko JM, O'Dorisio TM, Osei K.
    Journal: Diabet Med; 1991 May; 8(4):385-7. PubMed ID: 1830262.
    Abstract:
    Two Type 1 diabetic patients with brittle diabetes were successfully treated using continuous SC octreotide (Sandostatin) infusion (200 micrograms 24-h-1) for 6 months and 12 months. When the analogue was discontinued, rapid deterioration in glucose control and ketonuria recurred in one patient and diabetic ketoacidosis in the other. These were corrected after reinstitution of the analogue.
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