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  • Title: Quality of life in patients with chronic obstructive pulmonary disease: the predictive validity of the BODE index.
    Author: Medinas-Amorós M, Alorda C, Renom F, Rubí M, Centeno J, Ferrer V, Gorriz T, Mas-Tous C, Ramis F.
    Journal: Chron Respir Dis; 2008; 5(1):7-11. PubMed ID: 18303096.
    Abstract:
    BACKGROUND: Chronic obstructive pulmonary disease (COPD) is currently the fourth cause of mortality and morbility in the developed world. Patients with COPD experience a progressive deterioration of health-related quality of life (HRQOL). A new model of severity classification, the body mass index, bronchial obstruction, dyspnoea, exercise (BODE) index, has recently been proposed. OBJECTIVE: To evaluate the relationship between HRQOL and the BODE index, and the predictive ability of BODE on HRQOL measurements. METHODS: Two HRQOL questionnaires were administered, namely the Nottingham Health Profile (NHP) and St George's Respiratory Questionnaire (SGRQ), in a sample of 67 patients with severe COPD. RESULTS: Pearsonś correlation coefficient analysis shows a positive correlation between the BODE index and the total scores of the specific (P < 0.001), and general HRQOL (P < 0.001); the analysis shows a significant correlation between the BODE index and the subscales of symptoms, activity and impact of SGRQ (P < 0.001) and the subscales energy and physical mobility of the NHP (P < 0.001). The regression analysis shows that the BODE index is a significant predictor of HRQOL, explaining 46,1% of the total score of the SGRQ (P < 0.001) and 14.8% of the total score of the NHP (P < 0.001). CONCLUSIONS: The BODE index is good at predicting the worsening of HRQOL in patients with severe COPD.
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