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  • Title: [Results of treatment in patients with destructive pulmonary tuberculosis without consideration of drug sensitivity in Mycobacterium tuberculosis].
    Author: Abashev IM, Kozlova AI, Ivanova LN.
    Journal: Probl Tuberk Bolezn Legk; 2008; (1):33-5. PubMed ID: 18318228.
    Abstract:
    Treatment of 63 patients having infiltrative and disseminated pulmonary tuberculosis attended by decay and bacterial excretion with 4 essential drugs (isoniazid, rifadine, pyrazinamide, ethambutol) and, in disseminated processes, additionally with streptomycin without determining their drug sensitivity contributed to the cessation of sputum acid-resistant mycobacteria in 96.8% and to cavity cicatrisation in 77.8%. Irregular use of izoniazid and rifadine during continued treatment is one of the reasons for the low rates of cavity resolution.
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