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  • Title: Antifungal and antimycobacterial activity of 1-(3,5-diaryl-4,5-dihydro-1H-pyrazol-4-yl)-1H-imidazole derivatives.
    Author: Zampieri D, Mamolo MG, Laurini E, Scialino G, Banfi E, Vio L.
    Journal: Bioorg Med Chem; 2008 Apr 15; 16(8):4516-22. PubMed ID: 18321714.
    Abstract:
    1-(3,5-Diaryl-4,5-dihydro-1H-pyrazol-4-yl)-1H-imidazole derivatives were synthesized and tested for their in vitro antifungal and antimycobacterial activities. These imidazole derivatives showed an excellent antifungal activity against a clinical strain of Candida albicans and an interesting antitubercular activity against Mycobacterium tuberculosis H(37)Rv reference strain.
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