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  • Title: Is exercise-induced U-wave inversion predictive of proximal left anterior descending coronary artery disease?
    Author: Costantini M, Capone S, Tondo A, Oreto G.
    Journal: J Electrocardiol; 2008; 41(2):99-101. PubMed ID: 18328331.
    Abstract:
    A 66-year-old patient with a recent history of chest pain was submitted to exercise test. The rest electrocardiogram was normal, but during effort, a striking U-wave inversion in the chest leads occurred, not associated with any ST-segment change. Coronary angiogram demonstrated a severe proximal narrowing of the left anterior descending coronary artery. Effort-induced U-wave inversion in the precordial leads has long been recognized as a marker of stenosis of the left anterior descending coronary artery, but this pattern is seldom taken into account.
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