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  • Title: Hop1 and the meiotic DNA-damage response.
    Author: Hunter N.
    Journal: Cell; 2008 Mar 07; 132(5):731-2. PubMed ID: 18329359.
    Abstract:
    During the DNA-damage response, adaptor proteins mediate signaling between the PI3K-like sensor kinases, ATM and ATR, and serine/threonine effector kinases. Carballo et al. (2008) now show that the chromosomal protein Hop1 mediates PI3K-like kinase signaling during the repair of DNA double-strand breaks (DSBs) in meiosis.
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